Optoacoustic imaging is increasingly attracting the attention of the biomedical research community due to its excellent spatial and temporal resolution, centimeter scale penetration into living tissues, versatile endogenous and exogenous optical absorption contrast. State-of-the-art implementations of multi-spectral optoacoustic tomography (MSOT) are based on multi-wavelength excitation of tissues to visualize specific molecules within opaque tissues. As a result, the technology can noninvasively deliver structural, functional, metabolic, and molecular information from living tissues. The talk covers most recent advances pertaining ultrafast imaging instrumentation, multi-modal combinations with optical and ultrasound methods, intelligent reconstruction algorithms as well as smart optoacoustic contrast and sensing approaches. Our current efforts are also geared toward exploring potential of the technique in studying multi-scale dynamics of the brain and heart, monitoring of therapies, fast tracking of cells and targeted molecular imaging applications. MSOT further allows for a handheld operation thus offers new level of precision for clinical diagnostics of patients in a number of indications, such as breast and skin lesions, inflammatory diseases and cardiovascular diagnostics.
Biography: Daniel Razansky is Full Professor of Biomedical Imaging at the University and ETH Zurich. He studied Electrical and Biomedical Engineering at the Technion - Israel Institute of Technology and did his postdoc in bio-optics at the Harvard Medical School. He was previously Professor of Molecular Imaging Engineering at the Technical University of Munich and Helmholtz Center Munich. His lab pioneered a number of new bio-imaging modalities successfully commercialized and installed in many labs and clinical facilities around the globe, among them the multi-spectral optoacoustic tomography (MSOT) and hybrid optoacoustic ultrasound (OPUS). Prof. Razansky’s research has been awarded the German Innovation Prize, three ERC grants, and multiple grants from the NIH, the German and Swiss Science Foundations and the Human Frontiers Science Program. He is also an elected Fellow of the Optical Society of America (OSA) and the International Society for Optics and Photonics (SPIE).