Active microswimmers have attracted considerable attention because of their potential applications, especially for biomedical applications such as cargo transport, targeted drug delivery, biosensors, and environment remediation. The main objective of our team is to develop new material platforms and systematic fabrication methods for microswimmer design and multifunctional cargo carriers, which can be applied to both synthetic catalytically driven and biohybrid microswimmers. With such new swimmer designs and methods, the swimming behavior of the microswimmers under various external conditions is investigated.