Considerable attention is being paid to flexible sensors and actuators due to their various healthcare, human-machine interfaces, and soft robotic applications. Stretchable and wearable sensors can be attached onto the clothing or even directly mounted on the human skin for the real-time monitoring of human activities. Additionally, flexible sensors would be beneficial in soft robotics as feedback controllers for locomotion of soft-bodied robots as well as robotic soft sensory skins, allowing soft robots to sense the surrounding environment. In this project, we develop soft and high-performance sensors using new functional materials and smart structures. Additionally, we address the challenge of the conformal attachment of wearable sensors to the rough and textured surfaces like skin by using bioinspired composite microfibers.